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Erik K. St. Louis, Barry E. Gidal, Thomas R. Henry, Yevgenya Kaydanova, Allan Krumholz, Paul H. McCabe, Georgia D. Montouris, William E. Rosenfeld, Brien J. Smith, John M. Stern, Elizabeth J. Waterhouse, Richard M. Schulz, William R. Garnett, Thomas Bramley

Research output: Contribution to journalArticle

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Gym Sport KKLM Athletic Workout Jogging Women's Walking warm Chu Red09 Sneakers Fitness Shoes Fashion Running Abstract

To develop expert consensus for conversion between antiepileptic drug (AED) monotherapies, an 11-member panel used the Delphi Technique over three rounds to: (1) identify relevant issues, (2) vote on the issues, and (3) develop consensus. The panel agreed on the basic principle to taper the existing AED only after a presumably efficacious dose of the planned AED was reached. Application is modified by adverse effects possibly attributable to the existing drug, in which case earlier or more rapid tapering of the existing drug should be considered. Patients with uncontrolled seizures, as well as seizure-free patients for whom driving privileges are a consideration, may benefit from slower tapering by smaller dosage decrements of the existing AED. For 10 of the 12 AEDs considered, the panel made titration recommendations concerning initial and target doses for the planned AED, supplementing limited data in the prescribing information. This expert guidance will aid in the period of transitional polytherapy with AEDs from monotherapy to monotherapy.

Language English (US)
Pages 222-234
Number of pages Fashion Chu Gym Jogging Workout Athletic Fitness warm Running Women's Walking Shoes KKLM Red09 Sport Sneakers 13
Journal Epilepsy and Behavior
Volume 11
Issue number 2
Women's Walking KKLM Sport Red09 Fitness Jogging Fashion Sneakers Running Shoes Chu Athletic warm Gym Workout DOIs
Sport Fashion Jogging Walking Athletic Workout KKLM Running Fitness Red09 Sneakers warm Gym Chu Shoes Women's State Published - Sep 2007
warm Athletic Jogging KKLM Shoes Gym Sneakers Red09 Workout Fashion Chu Fitness Sport Women's Walking Running Externally published Yes


  • Antiepileptic drugs
  • Conversion
  • Delphi Technique
  • Epilepsy
  • Expert opinion
  • Monotherapy
  • Polytherapy

ASJC Scopus subject areas

  • Clinical Neurology
  • Behavioral Neuroscience
  • Neurology

Cite this

KKLM Walking Women's Fashion Workout Jogging Running Red09 warm Fitness Shoes Sneakers Sport Gym Chu Athletic St. Louis, E. K.White Bike Chrome Shoes Garneau Louis O4wqPxTI4, Gidal, B. E., Henry, T. R., Kaydanova, Y., Krumholz, A., McCabe, P. H., ... Bramley, T. (2007). Conversions between monotherapies in epilepsy: Expert consensus. Epilepsy and Behavior, 11(2), 222-234. DOI: 10.1016/j.yebeh.2007.04.007
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