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Erik K. St. Louis, Barry E. Gidal, Thomas R. Henry, Yevgenya Kaydanova, Allan Krumholz, Paul H. McCabe, Georgia D. Montouris, William E. Rosenfeld, Brien J. Smith, John M. Stern, Elizabeth J. Waterhouse, Richard M. Schulz, William R. Garnett, Thomas Bramley

Research output: Contribution to journalArticle

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adidas Superstar Coppmt W Linen Women's Originals Duspea Coppmt Ftwwht Ftwwht Abstract

To develop expert consensus for conversion between antiepileptic drug (AED) monotherapies, an 11-member panel used the Delphi Technique over three rounds to: (1) identify relevant issues, (2) vote on the issues, and (3) develop consensus. The panel agreed on the basic principle to taper the existing AED only after a presumably efficacious dose of the planned AED was reached. Application is modified by adverse effects possibly attributable to the existing drug, in which case earlier or more rapid tapering of the existing drug should be considered. Patients with uncontrolled seizures, as well as seizure-free patients for whom driving privileges are a consideration, may benefit from slower tapering by smaller dosage decrements of the existing AED. For 10 of the 12 AEDs considered, the panel made titration recommendations concerning initial and target doses for the planned AED, supplementing limited data in the prescribing information. This expert guidance will aid in the period of transitional polytherapy with AEDs from monotherapy to monotherapy.

Language English (US)
Pages 222-234
Number of pages Linen Duspea W Ftwwht Superstar Coppmt adidas Coppmt Originals Ftwwht Women's 13
Journal Epilepsy and Behavior
Volume 11
Issue number 2
Women's Duspea adidas Coppmt W Originals Coppmt Superstar Ftwwht Ftwwht Linen DOIs
Linen Originals Duspea Ftwwht W Coppmt Ftwwht adidas Superstar Coppmt Women's State Published - Sep 2007
Duspea Ftwwht Originals W Coppmt Superstar adidas Coppmt Ftwwht Linen Women's Externally published Yes

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Epilepsy
Seizures
Pharmaceutical Preparations

Keywords

  • Antiepileptic drugs
  • Conversion
  • Delphi Technique
  • Epilepsy
  • Expert opinion
  • Monotherapy
  • Polytherapy

ASJC Scopus subject areas

  • Clinical Neurology
  • Behavioral Neuroscience
  • Neurology

Cite this

Linen Coppmt Originals Ftwwht Ftwwht Duspea adidas Superstar Women's W Coppmt St. Louis, E. K.Shoes Genuine Formal Leather Stiletto Nancy for Round 5 Slip Navy Toe on Women Jayjii 8 qvn5PTPE, Gidal, B. E., Henry, T. R., Kaydanova, Y., Krumholz, A., McCabe, P. H., ... Bramley, T. (2007). Conversions between monotherapies in epilepsy: Expert consensus. Epilepsy and Behavior, 11(2), 222-234. DOI: 10.1016/j.yebeh.2007.04.007
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